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>   home   >   Products   >   Primary Antibodies   >   MAN1B1 Antibody (monoclonal) (M01)   

MAN1B1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant MAN1B1.

  • WB - MAN1B1 Antibody (monoclonal) (M01) AT2770a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - MAN1B1 Antibody (monoclonal) (M01) AT2770a
    MAN1B1 monoclonal antibody (M01), clone 6B1. Western Blot analysis of MAN1B1 expression in HepG2 ( (Cat # AT2770a )
  • WB - MAN1B1 Antibody (monoclonal) (M01) AT2770a
    MAN1B1 monoclonal antibody (M01), clone 6B1. Western Blot analysis of MAN1B1 expression in LNCaP ( (Cat # AT2770a )
  • WB - MAN1B1 Antibody (monoclonal) (M01) AT2770a
    MAN1B1 monoclonal antibody (M01), clone 6B1 Western Blot analysis of MAN1B1 expression in A-431 ( (Cat # AT2770a )
  • IHC - MAN1B1 Antibody (monoclonal) (M01) AT2770a
    Immunoperoxidase of monoclonal antibody to MAN1B1 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3 ug/ml]
  • E - MAN1B1 Antibody (monoclonal) (M01) AT2770a
    Detection limit for recombinant GST tagged MAN1B1 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UKM7
Other Accession NM_016219
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 6B1
Calculated MW 79580 Da
Additional Information
Gene ID 11253
Other Names Endoplasmic reticulum mannosyl-oligosaccharide 1, 2-alpha-mannosidase, ER alpha-1, 2-mannosidase, ER mannosidase 1, ERMan1, Man9GlcNAc2-specific-processing alpha-mannosidase, Mannosidase alpha class 1B member 1, MAN1B1
Target/Specificity MAN1B1 (NP_057303, 112 a.a. ~ 211 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMAN1B1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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Polymorphism in the endoplasmic reticulum mannosidase I (MAN1B1) gene is not associated with liver disease in individuals homozygous for the Z variant of the alpha1-antitrypsin protease inhibitor (PiZZ individuals). Chappell S, et al. Hepatology, 2009 Oct. PMID 19739260.Single nucleotide polymorphism-mediated translational suppression of endoplasmic reticulum mannosidase I modifies the onset of end-stage liver disease in alpha1-antitrypsin deficiency. Pan S, et al. Hepatology, 2009 Jul. PMID 19444872.Theory and computation show that Asp463 is the catalytic proton donor in human endoplasmic reticulum alpha-(1-->2)-mannosidase I. Cant? D, et al. Carbohydr Res, 2008 Sep 8. PMID 18619586.Endoplasmic reticulum (ER) mannosidase I is compartmentalized and required for N-glycan trimming to Man5-6GlcNAc2 in glycoprotein ER-associated degradation. Avezov E, et al. Mol Biol Cell, 2008 Jan. PMID 18003979.Stimulation of ERAD of misfolded null Hong Kong alpha1-antitrypsin by Golgi alpha1,2-mannosidases. Hosokawa N, et al. Biochem Biophys Res Commun, 2007 Oct 26. PMID 17727818.

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$ 350.00
Cat# AT2770a
Availability: 7-10 days
Bulk Size

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