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MEFV Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant MEFV.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O15553 |
| Other Accession | NM_000243 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 4E7 |
| Calculated MW | 86444 Da |
| Gene ID | 4210 |
|---|---|
| Other Names | Pyrin, Marenostrin, MEFV, MEF |
| Target/Specificity | MEFV (NP_000234, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | MEFV Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome.
References
An approach based on a genome-wide association study reveals candidate loci for narcolepsy. Shimada M, et al. Hum Genet, 2010 Oct. PMID 20677014.Association of familial mediterranean fever-related MEFV gene variations with ankylosing spondylitis. Cosan F, et al. Arthritis Rheum, 2010 Jul 28. PMID 20669279.Mediterranean fever (MEFV) gene mutation frequency is not increased in adults with rheumatic heart disease. Simsek I, et al. Clin Rheumatol, 2010 Jul 20. PMID 20645115.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.MEFV E148Q polymorphism is associated with Henoch-Sch?nlein purpura in Chinese children. He X, et al. Pediatr Nephrol, 2010 Oct. PMID 20602240.
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