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MGRN1 Antibody (monoclonal) (M07)
Mouse monoclonal antibody raised against a partial recombinant MGRN1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF |
|---|---|
| Primary Accession | O60291 |
| Other Accession | NM_015246 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 30 |
| Calculated MW | 60753 Da |
| Gene ID | 23295 |
|---|---|
| Other Names | E3 ubiquitin-protein ligase MGRN1, 632-, Mahogunin RING finger protein 1, RING finger protein 156, MGRN1, KIAA0544, RNF156 |
| Target/Specificity | MGRN1 (NP_056061, 477 a.a. ~ 576 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | MGRN1 Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Mahogunin (MGRN1) is a C3HC4 RING-containing protein with E3 ubiquitin ligase activity in vitro.
References
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Galphas. P?rez-Oliva AB, et al. J Biol Chem, 2009 Nov 13. PMID 19737927.Functional depletion of mahogunin by cytosolically exposed prion protein contributes to neurodegeneration. Chakrabarti O, et al. Cell, 2009 Jun 12. PMID 19524515.Pigmentation-related genes and their implication in malignant melanoma susceptibility. Fernandez LP, et al. Exp Dermatol, 2009 Jul. PMID 19320733.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.
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