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NDUFA9 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant NDUFA9.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IF |
|---|---|
| Primary Accession | Q16795 |
| Other Accession | NM_005002 |
| Reactivity | Human, Mouse, Rat |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3D7 |
| Calculated MW | 42510 Da |
| Gene ID | 4704 |
|---|---|
| Other Names | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial, Complex I-39kD, CI-39kD, NADH-ubiquinone oxidoreductase 39 kDa subunit, NDUFA9, NDUFS2L |
| Target/Specificity | NDUFA9 (NP_004993, 303 a.a. ~ 377 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | NDUFA9 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. A pseudogene has been identified on chromosome 12.
References
Polymorphisms in mitochondrial genes and prostate cancer risk. Wang L, et al. Cancer Epidemiol Biomarkers Prev, 2008 Dec. PMID 19064571.The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. Persson B, et al. Chem Biol Interact, 2009 Mar 16. PMID 19027726.Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. Starr JM, et al. Mech Ageing Dev, 2008 Dec. PMID 18977241.GRIM-19 is essential for maintenance of mitochondrial membrane potential. Lu H, et al. Mol Biol Cell, 2008 May. PMID 18287540.A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. Harris SE, et al. BMC Genet, 2007 Jul 2. PMID 17601350.
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