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NGB Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a full length recombinant NGB.

     
  • WB - NGB Antibody (monoclonal) (M02) AT3045a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (42.35 KDa) .
    detail
  • E - NGB Antibody (monoclonal) (M02) AT3045a
    Detection limit for recombinant GST tagged NGB is approximately 0.1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NPG2
Other Accession BC032509
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 1A11-A9
Calculated MW 16933 Da
Additional Information
Gene ID 58157
Other Names Neuroglobin, NGB
Target/Specificity NGB (AAH32509, 1 a.a. ~ 151 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsNGB Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions.

References

Neuroglobin genetic polymorphisms and their relationship to functional outcomes after traumatic brain injury. Chuang PY, et al. J Neurotrauma, 2010 Jun. PMID 20345238.Spectroscopic study on acid-induced unfolding and refolding of apo-neuroglobin. Mu J, et al. Spectrochim Acta A Mol Biomol Spectrosc, 2010 May. PMID 20227336.Neuroglobin protects nerve cells from apoptosis by inhibiting the intrinsic pathway of cell death. Raychaudhuri S, et al. Apoptosis, 2010 Apr. PMID 20091232.Neuroglobin expression in ischemic stroke. Jin K, et al. Stroke, 2010 Mar. PMID 20075359.Unusual stability of human neuroglobin at low pH--molecular mechanisms and biological significance. Picotti P, et al. FEBS J, 2009 Dec. PMID 19860834.

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$ 350.00
Cat# AT3045a
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Availability: 7-10 days
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