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NOVA1 Antibody (monoclonal) (M10)

Mouse monoclonal antibody raised against a partial recombinant NOVA1.

     
  • WB - NOVA1 Antibody (monoclonal) (M10) AT3082a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.52 KDa) .
    detail
  • WB - NOVA1 Antibody (monoclonal) (M10) AT3082a
    NOVA1 monoclonal antibody (M10), clone 5D9. Western Blot analysis of NOVA1 expression in PC-12 ( (Cat # AT3082a )
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P51513
Other Accession NM_002515
Reactivity Human, Rat
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 5D9
Calculated MW 51727 Da
Additional Information
Gene ID 4857
Other Names RNA-binding protein Nova-1, Neuro-oncological ventral antigen 1, Onconeural ventral antigen 1, Paraneoplastic Ri antigen, Ventral neuron-specific protein 1, NOVA1
Target/Specificity NOVA1 (NP_002506, 408 a.a. ~ 507 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsNOVA1 Antibody (monoclonal) (M10) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.

References

Genome-wide association study of antipsychotic-induced parkinsonism severity among schizophrenia patients. Alkelai A, et al. Psychopharmacology (Berl), 2009 Oct. PMID 19680635.Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. Vasan RS, et al. JAMA, 2009 Jul 8. PMID 19584346.Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. Anney RJ, et al. Am J Med Genet B Neuropsychiatr Genet, 2008 Dec 5. PMID 18951430.Paraneoplastic antibody during follow-up of a patient with anti-Ri-associated paraneoplastic neurological syndrome. Stich O, et al. Acta Neurol Scand, 2009 May. PMID 18822086.Post-transcriptional regulation of neuro-oncological ventral antigen 1 by the neuronal RNA-binding proteins ELAV. Ratti A, et al. J Biol Chem, 2008 Mar 21. PMID 18218628.

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$ 350.00
Cat# AT3082a
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