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PASD1 Antibody (monoclonal) (M06)

Mouse monoclonal antibody raised against a full length recombinant PASD1.

     
  • WB - PASD1 Antibody (monoclonal) (M06) AT3186a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37 KDa) .
    detail
  • WB - PASD1 Antibody (monoclonal) (M06) AT3186a
    PASD1 monoclonal antibody (M06), clone 1G12 Western Blot analysis of PASD1 expression in HeLa ( (Cat # AT3186a )
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q8IV76
Other Accession NM_173493
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 1G12
Calculated MW 87428 Da
Additional Information
Gene ID 139135
Other Names PAS domain-containing protein 1, Cancer/testis antigen 63, CT63, OX-TES-1, PASD1
Target/Specificity PASD1 (NP_775764, 1 a.a. ~ 100 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPASD1 Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)
citation

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Background

This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma.

References

Elevated expression levels of testis-specific genes TEX101 and SPATA19 in basal cell carcinoma and their correlation with clinical and pathological features. Ghafouri-Fard S, et al. Br J Dermatol, 2010 Apr. PMID 19886887.Cytolytic T-cell response to the PASD1 cancer testis antigen in patients with diffuse large B-cell lymphoma. Ait-Tahar K, et al. Br J Haematol, 2009 Aug. PMID 19552722.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.PASD1 is a potential multiple myeloma-associated antigen. Sahota SS, et al. Blood, 2006 Dec 1. PMID 17114574.PASD1, a DLBCL-associated cancer testis antigen and candidate for lymphoma immunotherapy. Cooper CD, et al. Leukemia, 2006 Dec. PMID 17024112.

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$ 350.00
Cat# AT3186a
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