PCDH8 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant PCDH8.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, E |
---|---|
Primary Accession | O95206 |
Other Accession | NM_002590 |
Reactivity | Human |
Host | mouse |
Clonality | Monoclonal |
Isotype | IgG1 Kappa |
Clone Names | 6A8 |
Calculated MW | 113019 Da |
Gene ID | 5100 |
---|---|
Other Names | Protocadherin-8, Arcadlin, PCDH8 |
Target/Specificity | PCDH8 (NP_002581, 32 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Dilution | WB~~1:500~1000 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | PCDH8 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails.
References
1.Identification of Cell Surface Targets through Meta-analysis of Microarray Data.Haeberle H, Dudley JT, Liu JT, Butte AJ, Contag CH.Neoplasia (2012) 14, 666?V669
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