RFFL Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RFFL.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | Q8WZ73 |
| Other Accession | NM_001017368 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3A4 |
| Calculated MW | 40514 Da |
| Gene ID | 117584 |
|---|---|
| Other Names | E3 ubiquitin-protein ligase rififylin, 632-, Caspase regulator CARP2, Caspases-8 and -10-associated RING finger protein 2, CARP-2, FYVE-RING finger protein Sakura, Fring, RING finger and FYVE-like domain-containing protein 1, RING finger protein 189, RING finger protein 34-like, RFFL (HGNC:24821), RNF189, RNF34L |
| Target/Specificity | RFFL (NP_001017368, 2 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RFFL Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |

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References
An approach based on a genome-wide association study reveals candidate loci for narcolepsy. Shimada M, et al. Hum Genet, 2010 Oct. PMID 20677014.Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. Hosgood HD 3rd, et al. Occup Environ Med, 2009 Dec. PMID 19773279.Common variants at ten loci influence QT interval duration in the QTGEN Study. Newton-Cheh C, et al. Nat Genet, 2009 Apr. PMID 19305408.CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kappaB activation. Liao W, et al. Curr Biol, 2008 May 6. PMID 18450452.CARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing MDM2. Yang W, et al. Cell Cycle, 2008 Mar 1. PMID 18382127.
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