SLA2 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant SLA2.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9H6Q3 |
Other Accession | BC042041 |
Reactivity | Human |
Host | mouse |
Clonality | Monoclonal |
Isotype | IgG1 kappa |
Clone Names | 3G5 |
Calculated MW | 28585 Da |
Gene ID | 84174 |
---|---|
Other Names | Src-like-adapter 2, Modulator of antigen receptor signaling, MARS, Src-like adapter protein 2, SLAP-2, SLA2, C20orf156, SLAP2 |
Target/Specificity | SLA2 (AAH42041, 1 a.a. ~ 261 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Dilution | WB~~1:500~1000 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | SLA2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the SLAP family of adapter proteins. The encoded protein may play an important receptor-proximal role in downregulating T and B cell-mediated responses and inhibits antigen receptor-induced calcium mobilization. This protein interacts with Cas-Br-M (murine) ecotropic retroviral transforming sequence c. Two transcript variants encoding distinct isoforms have been identified for this gene.
References
The Src-like adaptor protein 2 regulates colony-stimulating factor-1 receptor signaling and down-regulation. Pakuts B, et al. J Biol Chem, 2007 Jun 22. PMID 17353186.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.Cloning and characterization of human Src-like adaptor protein 2 and a novel splice isoform, SLAP-2-v. Loreto MP, et al. Oncogene, 2003 Jan 16. PMID 12527895.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
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