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SLC36A2 Antibody (monoclonal) (M04)
Mouse monoclonal antibody raised against a partial recombinant SLC36A2.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q495M3 |
| Other Accession | NM_181776 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 2H3 |
| Calculated MW | 53216 Da |
| Gene ID | 153201 |
|---|---|
| Other Names | Proton-coupled amino acid transporter 2, Proton/amino acid transporter 2, Solute carrier family 36 member 2, Tramdorin-1, SLC36A2, PAT2, TRAMD1 |
| Target/Specificity | SLC36A2 (NP_861441, 1 a.a. ~ 71 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | SLC36A2 Antibody (monoclonal) (M04) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a pH-dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline. Mutations in this gene are associated with iminoglycinuria and hyperglycinuria.
References
Fine mapping of the CELIAC2 locus on chromosome 5q31-q33 in the Finnish and Hungarian populations. Koskinen LL, et al. Tissue Antigens, 2009 Nov. PMID 19845895.Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. Trynka G, et al. Gut, 2009 Aug. PMID 19240061.Amino acid transport across mammalian intestinal and renal epithelia. Br?er S. Physiol Rev, 2008 Jan. PMID 18195088.Organization and expression of the SLC36 cluster of amino acid transporter genes. Bermingham JR Jr, et al. Mamm Genome, 2004 Feb. PMID 15058382.The proton/amino acid cotransporter PAT2 is expressed in neurons with a different subcellular localization than its paralog PAT1. Rubio-Aliaga I, et al. J Biol Chem, 2004 Jan 23. PMID 14600155.
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