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TKTL1 monoclonal antibody (M01), clone 1C10
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, E |
|---|---|
| Primary Accession | P51854 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 1C10 |
| Calculated MW | 65333 Da |
| Gene ID | 8277 |
|---|---|
| Other Names | Transketolase-like protein 1, Transketolase 2, TK 2, Transketolase-related protein, TKTL1, TKR, TKT2 |
| Target/Specificity | TKTL1 (AAH25382, 1 a.a. ~ 596 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:1000 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | TKTL1 monoclonal antibody (M01), clone 1C10 is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Expression of transketolase-like 1 protein (TKTL1) in human endometrial cancer. Krockenberger M, et al. Anticancer Res, 2010 May. PMID 20592357.TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization. Sun W, et al. Clin Cancer Res, 2010 Feb 1. PMID 20103683.Glycolytic phenotype in breast cancer: activation of Akt, up-regulation of GLUT1, TKTL1 and down-regulation of M2PK. Schmidt M, et al. J Cancer Res Clin Oncol, 2010 Feb. PMID 19655166.Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia. Sanna S, et al. Hum Mol Genet, 2009 Jul 15. PMID 19419973.Overexpression of transketolase-like gene 1 is associated with cell proliferation in uterine cervix cancer. Chen H, et al. J Exp Clin Cancer Res, 2009 Mar 30. PMID 19331662.
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