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TWIST1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant TWIST1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IP |
|---|---|
| Primary Accession | Q15672 |
| Other Accession | NM_000474 |
| Reactivity | Human, Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 3E12 |
| Calculated MW | 20954 Da |
| Gene ID | 7291 |
|---|---|
| Other Names | Twist-related protein 1, Class A basic helix-loop-helix protein 38, bHLHa38, H-twist, TWIST1, BHLHA38, TWIST |
| Target/Specificity | TWIST1 (NP_000465, 100 a.a. ~ 202 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | TWIST1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue; in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.
References
1.Cellular migration and invasion uncoupled: Increased migration is not an inexorable consequence of EMT.Schaeffer D, Somarelli JA, Hanna G, Palmer GM, Garcia-Blanco MAMol Cell Biol. 2014 Jul 7. pii: MCB.00694-14.2.EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours.Bornachea O, Santos M, Martinez-Cruz AB, Garcia-Escudero R, Duenas M, Costa C, Segrelles C, Lorz C, Buitrago A, Saiz-Ladera C, Agirre X, Grande T, Paradela B, Maraver A, Ariza JM, Prosper F, Serrano M, Sanchez-Cespedes M, Paramio JM.Sci Rep. 2012;2:434. Epub 2012 May 31.3.Conversion of Helicobacter pylori CagA from senescence inducer to oncogenic driver through polarity-dependent regulation of p21.Saito Y, Murata-Kamiya N, Hirayama T, Ohba Y, Hatakeyama M.J Exp Med. 2010 Sep 27;207(10):2157-74. Epub 2010 Sep 20.
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