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In Vivo Ready™ Anti-Mouse IL-10 (JES5-2A5) Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FA |
|---|---|
| Isotype | Rat IgG1, kappa |
| Concentration | 2.0 mg/mL |
| Reactivity | Mouse |
| Formulation | 10 mM NaH2PO4, 150 mM NaCl, pH7.2 |
| Host | Rat |
| Alternative Name(s) | Interleukin-10, IL10 |
|---|---|
| Format | In Vivo Ready™ |
| Storage Conditions | 2-8°C |
Provided below are standard protocols that you may find useful for product applications.
Background
The JES5-2A5 antibody is specific for mouse IL-10. IL-10 has numerous biological activities including the ability to inhibit both the synthesis of Th1 cytokines and proliferation of T cells. In the mouse, IL-10 is produced by phagocytic cells, conventional dendritic, cells, T cells, B cells, and NK cells. The JES5-2A5 antibody is a neutralizing antibody.
References
Abrams JS, Roncarolo MG, Yssel H, Andersson U, Gleich GJ, Silver, JE. 1992. Immunol Rev. 127:5-24.
Sander B, Hoiden I, Andersson U, Moller E, Abrams JS. 1993. J Immunol Methods. 166(2):201-214.
Marchant A, Bruyns C, Vandenabeele P, Ducarme M, Gérard C, Delvaux A, De Groote D, Abramowicz D, Velu T, Goldman M. 1994. Eur J Immunol. 24(5):1167-1171.
Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F. 1999. J Exp Med. 190:995-1004.
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