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AMMECR1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9Y4X0 |
| Other Accession | Q9JHT5, Q5RAS7 |
| Reactivity | Human |
| Predicted | Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | H=35,31,25;M=36 KDa |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 9949 |
|---|---|
| Antigen Region | 271-298 aa |
| Other Names | AMME syndrome candidate gene 1 protein, AMMECR1 |
| Dilution | WB~~1:2000 |
| Target/Specificity | This AMMECR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-298 amino acids from the C-terminal region of human AMMECR1. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | AMMECR1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AMMECR1 |
|---|---|
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The exact function of this gene is not known, however, submicroscopic deletion of the X chromosome including this gene, COL4A5, and FACL4 genes, result in a contiguous gene deletion syndrome, the AMME complex (Alport syndrome, mental retardation, midface hypoplasia, and elliptocytosis). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Tajika, Y., et al. Proteins 58(2):501-503(2005)
Vitelli, F., et al. Genomics 55(3):335-340(1999)
Piccini, M., et al. Genomics 47(3):350-358(1998)
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