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RAE1 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - RAE1 Antibody (Center) AW5624-U100
    All lanes : Anti-RAE1 Antibody (Center) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: Jurkat whole cell lysate Lane 4: MCF-7 whole cell lysate Lane 5: SH-SY5Y whole cell lysate Lane 6: NIH/3T3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 41 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P78406
Other Accession Q5E9A4, Q4R6D2, Q8C570, Q3SWS8, A5GFN6, Q5RF99
Reactivity Human, Mouse
Predicted Bovine, Monkey, Rat, Pig
Host Rabbit
Clonality Polyclonal
Calculated MW H=41;M=41;R=41 KDa
Isotype Rabbit IgG
Antigen Source HUMAN
Additional Information
Gene ID 8480
Antigen Region 128-162 aa
Other Names mRNA export factor, Rae1 protein homolog, mRNA-associated protein mrnp 41, RAE1, MRNP41
Dilution WB~~1:2000
Target/Specificity This RAE1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 128-162 amino acids from the Central region of human RAE1.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRAE1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAE1
Synonyms MRNP41
Function Acts as a mRNA export factor involved in nucleocytoplasmic transport (PubMed:20498086, PubMed:33849972). Plays a role in mitotic bipolar spindle formation (PubMed:17172455). May function in attaching cytoplasmic mRNPs to the cytoskeleton both directly or indirectly (PubMed:17172455).
Cellular Location Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Nucleus envelope. Note=Recruited from interphase nuclei to spindle MTs during mitosis.
Research Areas
Citations (0)
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Background

Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.

References

Bharathi A.,et al.Gene 198:251-258(1997).
Kraemer D.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:9119-9124(1997).
Lu L.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 414:865-871(2001).

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$ 370.00
Cat# AW5624-U100
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