|Application ||WB, E|
|Calculated MW||105529 Da|
|Antigen Region||691-717 aa|
|Other Names||Protein HEG, Heart of glass, heg|
|Target/Specificity||This DANRE heg antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 691-717 amino acids from the C-terminal region of DANRE heg.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DANRE heg Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions.|
|Cellular Location||[Isoform 1]: Cell membrane; Single- pass type I membrane protein. Cell junction [Isoform 3]: Secreted.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions.
Mably J.D., et al. Curr. Biol. 13:2138-2147(2003).
Kleaveland B., et al. Nat. Med. 15:169-176(2009).
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