PP1R14C Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8TAE6 |
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Other Accession | NP_112211.1 |
Clone Names | 90805089 |
Gene ID | 81706 |
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Other Names | Protein phosphatase 1 regulatory subunit 14C, Kinase-enhanced PP1 inhibitor, PKC-potentiated PP1 inhibitory protein, Serologically defined breast cancer antigen NY-BR-81, PPP1R14C, KEPI |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PPP1R14C |
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Synonyms | KEPI |
Function | Inhibitor of the PP1 regulatory subunit PPP1CA. |
Cellular Location | Cytoplasm. Membrane; Peripheral membrane protein |
Tissue Location | Detected in breast cancer. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The degree of protein phosphorylation is regulated by abalance of protein kinase and phosphatase activities. Proteinphosphatase-1 (PP1; see MIM 176875) is a signal-transducingphosphatase that influences neuronal activity, protein synthesis,metabolism, muscle contraction, and cell division. PPP1R14C is aninhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]).[supplied byOMIM].
References
Daskalow, K., et al. Anticancer Res. 30(5):1573-1578(2010)Scholz, S.W., et al. Ann. Neurol. 65(5):610-614(2009)Burgner, D., et al. PLoS Genet. 5 (1), E1000319 (2009) :Mungall, A.J., et al. Nature 425(6960):805-811(2003)Liu, Q.R., et al. J. Biol. Chem. 277(15):13312-13320(2002)
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