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ARMCX2 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q7L311
Other Accession NP_808818.1, NP_055597.1
Clone Names 90819158
Additional Information
Gene ID 9823
Other Names Armadillo repeat-containing X-linked protein 2, ARM protein lost in epithelial cancers on chromosome X 2, Protein ALEX2, ARMCX2, ALEX2, KIAA0512
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARMCX2
Synonyms ALEX2, KIAA0512
Function May regulate the dynamics and distribution of mitochondria in neural cells.
Cellular Location Mitochondrion {ECO:0000250|UniProtKB:Q6A058}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8BHS6}; Single- pass membrane protein
Tissue Location Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not expressed in pancreas and ovarian carcinomas
Research Areas
Citations (0)
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Background

This gene encodes a member of the ALEX family of proteinsand may play a role in tumor suppression. The encoded proteincontains a potential N-terminal transmembrane domain and a singleArmadillo (arm) repeat. Other proteins containing the arm repeatare involved in development, maintenance of tissue integrity, andtumorigenesis. This gene is closely localized with other familymembers, including ALEX1 and ALEX3, on the X chromosome. Twoalternative transcripts that encode the same protein but differ inthe 5' UTR have been described. Additional alternative transcriptsmay exist but their full length natures have not been determined. Apseudogene for this locus is located on chromosome 7. [provided byRefSeq].

References

Ross, M.T., et al. Nature 434(7031):325-337(2005)Goehler, H., et al. Mol. Cell 15(6):853-865(2004)Kurochkin, I.V., et al. Biochem. Biophys. Res. Commun. 280(1):340-347(2001)

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$ 277.78
Cat# BP10163a
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