DYNLRB2 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8TF09 |
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Other Accession | NP_570967.1 |
Clone Names | 91216228 |
Gene ID | 83657 |
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Other Names | Dynein light chain roadblock-type 2, Dynein light chain 2B, cytoplasmic, Roadblock domain-containing protein 2, DYNLRB2, DNCL2B, DNLC2B, ROBLD2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DYNLRB2 |
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Synonyms | DNCL2B, DNLC2B, ROBLD2 |
Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. |
Cellular Location | Cytoplasm, cytoskeleton. |
Tissue Location | High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte |
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Provided below are standard protocols that you may find useful for product applications.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)Jin, Q., et al. J. Cell. Physiol. 221(3):707-715(2009)Meyre, D., et al. Nat. Genet. 41(2):157-159(2009)Pfister, K.K., et al. J. Cell Biol. 171(3):411-413(2005)
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