Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
CASC4 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6P4E1 |
|---|---|
| Other Accession | NP_816929.1 |
| Clone Names | 91201035 |
| Gene ID | 113201 |
|---|---|
| Other Names | Protein CASC4, Cancer susceptibility candidate gene 4 protein, CASC4 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GOLM2 (HGNC:24892) |
|---|---|
| Synonyms | CASC4 |
| Cellular Location | Membrane; Single-pass type II membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The increased expression level of this gene is associatedwith HER-2/neu proto-oncogene overexpression. Amplification andresulting overexpression of this proto-oncogene are found inapproximately 30% of human breast and 20% of human ovarian cancers.Further characterization of the product of this gene may yieldinsight into the fundamental biology and pathogenetic effects ofHER-2/neu overexpression in human breast and ovarian cancer cells.Alternatively spliced variants encoding different isoforms havebeen identified for this gene.
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Sato, T., et al. Onkologie 26(3):268-271(2003)Scheer, M., et al. Mund Kiefer Gesichtschir 7(3):138-145(2003)Oh, J.J., et al. Nucleic Acids Res. 27(20):4008-4017(1999)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
