DEN5A Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6IQ26 |
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Other Accession | NP_056028.2 |
Clone Names | 91201047 |
Gene ID | 23258 |
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Other Names | DENN domain-containing protein 5A, Rab6-interacting protein 1, Rab6IP1, DENND5A, KIAA1091, RAB6IP1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DENND5A |
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Synonyms | KIAA1091, RAB6IP1 |
Function | Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth (By similarity). |
Cellular Location | Golgi apparatus membrane {ECO:0000250|UniProtKB:Q6PAL8} |
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Provided below are standard protocols that you may find useful for product applications.
Background
May be involved in Rab6-mediated GTPase signaling.
References
Recacha, R., et al. Structure 17(1):21-30(2009)Olsen, J.V., et al. Cell 127(3):635-648(2006)Janoueix-Lerosey, I., et al. J. Biol. Chem. 270(24):14801-14808(1995)
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