DPP3 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9NY33 |
---|---|
Clone Names | 81006098 |
Gene ID | 10072 |
---|---|
Other Names | Dipeptidyl peptidase 3, Dipeptidyl aminopeptidase III, Dipeptidyl arylamidase III, Dipeptidyl peptidase III, DPP III, Enkephalinase B, DPP3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DPP3 |
---|---|
Function | Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin (PubMed:3233187, PubMed:1515063). Also cleaves Arg-Arg-beta-naphthylamide (in vitro) (PubMed:9425109, PubMed:3233187, PubMed:11209758). |
Cellular Location | Cytoplasm, cytosol |
Tissue Location | Detected in placenta (at protein level) (PubMed:3233187). Detected in erythrocytes (at protein level) (PubMed:1515063). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein that is a member of the M49family of metallopeptidases. This cytoplasmic protein binds asingle zinc ion with its zinc-binding motif (HELLGH) and haspost-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Prodipeptides from the N-termini of proteins. Increased activity ofthis protein is associated with endometrial and ovarian cancers.Alternate transcriptional splice variants have been characterized.
References
Shukla, A.A., et al. FEBS J. 277(8):1861-1875(2010)Salopek-Sondi, B., et al. Biol. Chem. 389(2):163-167(2008)Gevaert, K., et al. Proteomics 5(14):3589-3599(2005)Abramic, M., et al. Int. J. Biochem. Cell Biol. 36(3):434-446(2004)Hillman, R.T., et al. Genome Biol. 5 (2), R8 (2004) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.