TMEM201 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q5SNT2 |
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Clone Names | 100126174 |
Gene ID | 199953 |
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Other Names | Transmembrane protein 201, Spindle-associated membrane protein 1, TMEM201, NET5, SAMP1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TMEM201 |
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Synonyms | NET5, SAMP1 |
Function | Involved in nuclear movement during fibroblast polarization and migration. Proposed to be involved in actin-dependent nuclear movement via association with transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow (By similarity). Overexpression can recruit Ran GTPase to the nuclear periphery (PubMed:27541860). |
Cellular Location | [Isoform 2]: Nucleus inner membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton, spindle pole. Note=The C- terminal of isoform 2 is located on the nucleoplasmic side. During interphase, isoform 2 is distributed in the inner nuclear membrane in distinct micro-domains and during mitosis, it is found in the ER but it also localizes to the polar regions of the mitotic spindle |
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Provided below are standard protocols that you may find useful for product applications.
Background
Isoform SAMP1 may define a distinct membrane domain in the vicinity of the mitotic spindle.
References
Buch, C., et al. J. Cell. Sci. 122 (PT 12), 2100-2107 (2009) :
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