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SLC7A2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P52569 |
|---|---|
| Clone Names | 101008225 |
| Gene ID | 6542 |
|---|---|
| Other Names | Cationic amino acid transporter 2, CAT-2, CAT2, Low affinity cationic amino acid transporter 2, Solute carrier family 7 member 2, SLC7A2, ATRC2, CAT2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SLC7A2 (HGNC:11060) |
|---|---|
| Function | Functions as a permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L- homoarginine); the affinity for its substrates differs between isoforms created by alternative splicing (PubMed:28684763, PubMed:9174363). May play a role in classical or alternative activation of macrophages via its role in arginine transport (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed at high levels in the skeletal muscle, placenta and ovary. Expressed at intermediate levels in the liver and pancreas and at low levels in the kidney and heart |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). Plays a regulatory role in classical or alternative activation of macrophages (By similarity).
References
Chaturvedi, R., et al. Gastroenterology 139(5):1686-1698(2010)Visigalli, R., et al. J. Mol. Cell. Cardiol. 49(2):260-270(2010)Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :Jaeger, K., et al. Histochem. Cell Biol. 129(3):321-329(2008)Broer, S. Physiol. Rev. 88(1):249-286(2008)
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