XCR1 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P46094 |
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Clone Names | 101008027 |
Gene ID | 2829 |
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Other Names | Chemokine XC receptor 1, G-protein coupled receptor 5, Lymphotactin receptor, XC chemokine receptor 1, XCR1, CCXCR1, GPR5 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | XCR1 |
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Synonyms | CCXCR1, GPR5 |
Function | Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level. Receptor for XCL1/Lymphotactin. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a chemokine receptorbelonging to the G protein-coupled receptor superfamily. The familymembers are characterized by the presence of 7 transmembranedomains and numerous conserved amino acids. This receptor is mostclosely related to RBS11 and the MIP1-alpha/RANTES receptor. Ittransduces a signal by increasing the intracellular calcium ionslevel. The viral macrophage inflammatory protein-II is anantagonist of this receptor and blocks signaling. Two alternativelyspliced transcript variants encoding the same protein have beenfound for this gene.
References
Yamazaki, C., et al. Biochem. Biophys. Res. Commun. 397(4):756-761(2010)Crozat, K., et al. J. Exp. Med. 207(6):1283-1292(2010)Bachem, A., et al. J. Exp. Med. 207(6):1273-1281(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Luttichau, H.R. Virol. J. 5, 50 (2008) :
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