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SNRPD3 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P62318 |
|---|---|
| Clone Names | 100311223 |
| Gene ID | 6634 |
|---|---|
| Other Names | Small nuclear ribonucleoprotein Sm D3, Sm-D3, snRNP core protein D3, SNRPD3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SNRPD3 |
|---|---|
| Function | Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:25555158, PubMed:26912367, PubMed:28076346, PubMed:28502770, PubMed:28781166, PubMed:32494006). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28076346, PubMed:28502770, PubMed:28781166). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (PubMed:15146077, PubMed:33509932). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). |
| Cellular Location | Cytoplasm, cytosol. Nucleus. Note=SMN- mediated assembly into core snRNPs occurs in the cytosol before SMN- mediated transport to the nucleus to be included in spliceosomes |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the smallnuclear ribonucleoprotein core protein family. It is required forpre-mRNA splicing and small nuclear ribonucleoprotein biogenesis.
References
Gonsalvez, G.B., et al. J. Cell Biol. 178(5):733-740(2007)Ma, Y., et al. Structure 13(6):883-892(2005)Mahler, M., et al. Arthritis Res. Ther. 7 (1), R19-R29 (2005) :Ong, S.E., et al. Nat. Methods 1(2):119-126(2004)Ong, S.E., et al. Nat. Methods 1(2):119-126(2004)
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