D SUMO Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O97102 |
---|---|
Clone Names | 3030508 |
Gene ID | 33981 |
---|---|
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP1287b was selected from the C-terminal region of Drosophila SUMO. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | O97102 |
---|---|
Cellular Location | Nucleus {ECO:0000256|RuleBase:RU361190}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. In the development of Drosophila, SUMO plays a maternal role in anterior-posterior (A/P) polarity and patterning.
References
Muller S, et al., Nat Rev Mol Cell Biol. 2001 2(3):202-10 Review.Hochstrasser M. Cell. 2001 107(1):5-8. Review.Kahyo T, et al., Mol Cell. 2001 Sep;8(3):713-8.Yeh ET, et al., Gene. 2000 May 2;248(1-2):1-14. Review.Keane,M.M., et al., Oncogene 18 (22), 3365-3375 (1999)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.