CX001 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O96002 |
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Clone Names | 91208203 |
Other Names | Transmembrane protein 257, TMEM257, CXorf1 |
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Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13165b was selected from the C-term region of CX001. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CXorf1 {ECO:0000303|PubMed:9881668} |
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Cellular Location | Membrane; Multi-pass membrane protein |
Tissue Location | Brain. In the hippocampus it is mainly localized in the granular-cell layer of the dentate gyrus and in the CA2-CA3 subfields of Ammon's horn. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This intronless gene is expressed in the hippocampus andmaps close to a candidate region for several X-linked mentalretardation (XLMR) syndromes. It is conserved in primates, cow, andhorse, but not found in mouse and rat. The exact function of thisgene is not known, but on the basis of its physical location andexpression pattern, it is proposed to have an important function inthe brain.
References
Ross, M.T., et al. Nature 434(7031):325-337(2005)Redolfi, E., et al. DNA Cell Biol. 17(12):1009-1016(1998)
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