EEA1 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q15075 |
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Clone Names | 100430133 |
Gene ID | 8411 |
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Other Names | Early endosome antigen 1, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2, EEA1, ZFYVE2 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP14008c was selected from the Center region of EEA1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | EEA1 |
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Synonyms | ZFYVE2 |
Function | Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. |
Cellular Location | Cytoplasm. Early endosome membrane; Peripheral membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
EEA1 binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.
References
Mishra, A., et al. Proc. Natl. Acad. Sci. U.S.A. 107(24):10866-10871(2010)Selak, S., et al. Neuroscience 143(4):953-964(2006)Ahtiainen, L., et al. Exp. Cell Res. 312(9):1540-1553(2006)Cabezas, A., et al. Gene 371(1):34-41(2006)Araki, N., et al. Cell Struct. Funct. 31(2):145-157(2006)
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