Mouse Npr1 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P18293 |
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Clone Names | 110316298 |
Gene ID | 18160 |
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Other Names | Atrial natriuretic peptide receptor 1, Atrial natriuretic peptide receptor type A, ANP-A, ANPR-A, NPR-A, Guanylate cyclase A, GC-A, Npr1, Npra |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP14073a was selected from the N-term region of Mouse Npr1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | Npr1 |
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Synonyms | Npra |
Function | Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. |
Cellular Location | Membrane; Single-pass type I membrane protein. |

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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
References
Madhani, M., et al. Am. J. Physiol. Heart Circ. Physiol. 299 (3), H827-H836 (2010) :Panayiotou, C.M., et al. Br. J. Pharmacol. 160(8):2045-2054(2010)Ropero, A.B., et al. Endocrinology 151(8):3665-3674(2010)Tankersley, C.G., et al. Inhal Toxicol 22(8):695-707(2010)Long, L., et al. Neuro Endocrinol. Lett. 31(1):126-130(2010)

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