CNNM2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H8M5 |
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Clone Names | 81006034 |
Gene ID | 54805 |
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Other Names | Metal transporter CNNM2, Ancient conserved domain-containing protein 2, Cyclin-M2, CNNM2, ACDP2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CNNM2 |
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Synonyms | ACDP2 |
Function | Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Widely expressed. Expressed at higher level in brain, kidney and placenta, while it is weakly expressed in skeletal muscle. In the kidney, it is expressed in the distal convoluted tubule and the thick ascending limb of Henle loop |
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Provided below are standard protocols that you may find useful for product applications.
Background
CNNM2 is a divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity).
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Takeuchi, F., et al. Circulation 121(21):2302-2309(2010)Yasuno, K., et al. Nat. Genet. 42(5):420-425(2010)Simon-Sanchez, J., et al. Nat. Genet. 41(12):1308-1312(2009)Newton-Cheh, C., et al. Nat. Genet. 41(6):666-676(2009)
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