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P2RY14 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q15391 |
|---|---|
| Clone Names | 100525298 |
| Gene ID | 9934 |
|---|---|
| Other Names | P2Y purinoceptor 14, P2Y14, G-protein coupled receptor 105, UDP-glucose receptor, P2RY14, GPR105, KIAA0001 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | P2RY14 |
|---|---|
| Synonyms | GPR105, KIAA0001 |
| Function | Receptor for UDP-glucose and other UDP-sugar coupled to G- proteins. Not activated by ATP, ADP, UTP or ATP. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | Highest expression in the placenta, adipose tissue, stomach and intestine, intermediate levels in the brain, spleen, lung and heart, lowest levels in the kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
The product of this gene belongs to the family ofG-protein coupled receptors, which contains several receptorsubtypes with different pharmacological selectivity for variousadenosine and uridine nucleotides. This receptor is a P2Ypurinergic receptor for UDP-glucose and other UDP-sugars coupled toG-proteins. It has been implicated in extending the known immunesystem functions of P2Y receptors by participating in theregulation of the stem cell compartment, and it may also play arole in neuroimmune function. Two transcript variants encoding thesame protein have been identified for this gene. [provided byRefSeq].
References
Arase, T., et al. J. Immunol. 182(11):7074-7084(2009)Dovlatova, N., et al. Thromb. Haemost. 100(2):261-270(2008)Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)Ivanov, A.A., et al. Bioorg. Med. Chem. Lett. 17(3):761-766(2007)Ivanov, A.A., et al. J. Comput. Aided Mol. Des. 20 (7-8), 417-426 (2006) :
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