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PRSS16 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NQE7
Clone Names 100406103
Additional Information
Gene ID 10279
Other Names Thymus-specific serine protease, 34--, Serine protease 16, PRSS16, TSSP
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRSS16
Synonyms TSSP
Function Protease that may play a role in T-cell development.
Cellular Location Cytoplasmic vesicle. Note=Vesicular, either lysosomal or endosomal
Tissue Location Expressed predominantly in cortical thymic epithelial cells
Research Areas
Citations (0)
citation

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Background

This gene encodes a serine protease expressed exclusivelyin the thymus. It is thought to play a role in the alternativeantigen presenting pathway used by cortical thymic epithelial cellsduring the positive selection of T cells. The gene is found in thelarge histone gene cluster on chromosome 6, near the majorhistocompatibility complex (MHC) class I region. A secondtranscript variant has been described, but its full length naturehas not been determined.

References

Shi, J., et al. Nature 460(7256):753-757(2009)Stefansson, H., et al. Nature 460(7256):744-747(2009)Viken, M.K., et al. Genes Immun. 10(4):323-333(2009)Lie, B.A., et al. Hum. Immunol. 68(7):592-598(2007)Luther, C., et al. Genes Immun. 6(1):1-7(2005)

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$ 277.78
Cat# BP16588a
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