SLC7A14 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8TBB6 |
---|---|
Clone Names | 110808281 |
Gene ID | 57709 |
---|---|
Other Names | Probable cationic amino acid transporter, Solute carrier family 7 member 14, SLC7A14, KIAA1613 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SLC7A14 {ECO:0000303|PubMed:24670872, ECO:0000312|HGNC:HGNC:29326} |
---|---|
Function | Imports 4-aminobutanoate (GABA) into lysosomes. May act as a GABA sensor that regulates mTORC2-dependent INS signaling and gluconeogenesis. The transport mechanism and substrate selectivity remain to be elucidated. |
Cellular Location | Lysosome membrane; Multi-pass membrane protein. Note=Exhibits a punctated pattern in the cytoplasm, which partially ovelaps with lysosomes. |
Tissue Location | Expressed in skin fibroblasts. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
SLC7A14 (Solute carrier family 7 member 14) is thought to be a cationic amino acid transporter, belonging to the amino acid-polyamine-organocation (APC) superfamily.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.