FAM125A Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96EY5 |
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Clone Names | 91218172 |
Gene ID | 93343 |
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Other Names | Multivesicular body subunit 12A, CIN85/CD2AP family-binding protein, ESCRT-I complex subunit MVB12A, Protein FAM125A, MVB12A, CFBP, FAM125A |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MVB12A |
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Synonyms | CFBP, FAM125A |
Function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor. |
Cellular Location | Cytoplasm. Nucleus. Endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Late endosome membrane; Peripheral membrane protein Note=Colocalizes with F-actin. Some fraction may be nuclear |
Tissue Location | Ubiquitously expressed except in skeletal muscle. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor.
References
Tsunematsu, T., et al. Biochem. Biophys. Res. Commun. 399(2):232-237(2010)Konishi, H., et al. J. Biol. Chem. 281(39):28919-28931(2006)Konishi, H., et al. J. Biol. Chem. 281(39):28919-28931(2006)
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