BRD9 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H8M2 |
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Clone Names | 110811022 |
Gene ID | 65980 |
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Other Names | Bromodomain-containing protein 9, Rhabdomyosarcoma antigen MU-RMS-408, BRD9 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | BRD9 |
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Function | Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797). Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA- histone contacts within a nucleosome in an ATP-dependent manner (PubMed:29374058). Orchestrates also the RAD51-RAD54 complex formation and thereby plays a role in homologous recombination (HR) (PubMed:32457312). |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
BRD9 is a bromodomain containing protein, which are known to bind to acetylated lysine residues.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Scotto, L., et al. Mol. Cancer 7, 58 (2008) :Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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