AKR1E2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96JD6 |
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Clone Names | 110808070 |
Gene ID | 83592 |
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Other Names | 5-anhydro-D-fructose reductase, AF reductase, Aldo-keto reductase family 1 member C-like protein 2, Aldo-keto reductase family 1 member E2, LoopADR, Testis-specific protein, hTSP, AKR1E2, AKR1CL2, AKRDC1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | AKR1E2 |
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Synonyms | AKR1CL2, AKRDC1 |
Function | Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D- fructose (AF) to 1,5-anhydro-D-glucitol (By similarity). Has low NADPH- dependent reductase activity towards 9,10-phenanthrenequinone (in vitro) (PubMed:12604216, PubMed:15118078). |
Cellular Location | Cytoplasm. |
Tissue Location | Specifically expressed in testis (PubMed:12604216, PubMed:15118078). Expressed in testicular germ cells and testis interstitial cells (PubMed:15118078). |
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Provided below are standard protocols that you may find useful for product applications.
Background
AKR1E2 catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones (By similarity). Has low NADPH-dependent reductase activity towards 9,10-phenanthrenequinone (in vitro).
References
Clancy, R.M., et al. Arthritis Rheum. 62(11):3415-3424(2010)Lamesch, P., et al. Genomics 89(3):307-315(2007)Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)Azuma, Y., et al. Mol. Hum. Reprod. 10(7):527-533(2004)Nishinaka, T., et al. Chem. Biol. Interact. 143-144, 299-305 (2003) :
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