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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   NAT6 Antibody (Center) Blocking Peptide   

NAT6 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q93015
Clone Names 100603269
Additional Information
Gene ID 24142
Other Names N-acetyltransferase 6, 231-, Protein fusion-2, Protein fus-2, NAT6, FUS2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NAA80 {ECO:0000303|PubMed:29581253, ECO:0000312|HGNC:HGNC:30252}
Function N-alpha-acetyltransferase that specifically mediates the acetylation of the acidic amino terminus of processed forms of beta- and gamma-actin (ACTB and ACTG, respectively) (PubMed:30028079, PubMed:29581253). N-terminal acetylation of processed beta- and gamma- actin regulates actin filament depolymerization and elongation (PubMed:29581253). In vivo, preferentially displays N-terminal acetyltransferase activity towards acid N-terminal sequences starting with Asp-Asp-Asp and Glu-Glu-Glu (PubMed:30028079, PubMed:29581253). In vitro, shows high activity towards Met-Asp-Glu-Leu and Met-Asp-Asp-Asp (PubMed:10644992, PubMed:29581307). May act as a tumor suppressor (PubMed:10644992).
Cellular Location Cytoplasm, cytosol
Tissue Location Strongly expressed in heart and skeletal muscle, followed by brain and pancreas, with weak expression in kidney, liver, and lung and no expression in placenta.
Research Areas
Citations (0)

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Background

NAT6 seems to be involved in N-acetylation. Acts on peptides with a N-terminal Met followed by Asp/Glu/Asn. May act as a tumor suppressor.

References

Young, R.P., et al. Postgrad Med J 85(1008):515-524(2009)Muzny, D.M., et al. Nature 440(7088):1194-1198(2006)Duh, F.M., et al. Mol. Cell. Probes 18(1):39-44(2004)Shuttleworth, T.L., et al. J. Biol. Chem. 277(25):23008-23018(2002)Lerman, M.I., et al. Cancer Res. 60(21):6116-6133(2000)

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$ 277.78
Cat# BP18997c
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