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SPESP1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6UW49 |
|---|---|
| Clone Names | 110901156 |
| Gene ID | 246777 |
|---|---|
| Other Names | Sperm equatorial segment protein 1, ESP, Equatorial segment protein, SP-ESP, Glycosylated 38 kDa sperm protein C-7/8, SPESP1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SPESP1 (HGNC:15570) |
|---|---|
| Function | Involved in fertilization ability of sperm. |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Small proacrosomal granules (during the Golgi phase), enlarged acrosomal vesicles (during the cap phase), acrosome (during the elongating phase), equatorial segment of the acrosome (during the maturation phase) (PubMed:12773409). After acrosome reaction localizes to the equatorial segment region in both noncapacitated and capacitated, acrosome-reacted sperm (By similarity) {ECO:0000250|UniProtKB:Q9D5A0, ECO:0000269|PubMed:12773409} |
| Tissue Location | Highly expressed in testis, where it is localized in the acrosome of postmeiotic stages of spermiogenesis (round and elongating spermatids and in ejaculated spermatozoa) (at protein level). Poorly expressed in placenta and fetal lung |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The encoded protein is a human alloantigen involved insperm-egg binding and fusion.
References
Wolkowicz, M.J., et al. J. Androl. 29(3):272-282(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Wolkowicz, M.J., et al. Biol. Reprod. 69(3):735-745(2003)
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