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TOMM34 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q15785 |
|---|---|
| Clone Names | 110901210 |
| Gene ID | 10953 |
|---|---|
| Other Names | Mitochondrial import receptor subunit TOM34, hTom34, Translocase of outer membrane 34 kDa subunit, TOMM34, URCC3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TOMM34 |
|---|---|
| Synonyms | URCC3 |
| Function | Plays a role in the import of cytosolically synthesized preproteins into mitochondria. Binds the mature portion of precursor proteins. Interacts with cellular components, and possesses weak ATPase activity. May be a chaperone-like protein that helps to keep newly synthesized precursors in an unfolded import compatible state. |
| Cellular Location | Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side |
| Tissue Location | Ubiquitous. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is involved in the importof precursor proteins into mitochondria. The encoded protein has achaperone-like activity, binding the mature portion of unfoldedproteins and aiding their import into mitochondria. This protein,which is found in the cytoplasm and sometimes associated with theouter mitochondrial membrane, has a weak ATPase activity andcontains 6 TPR repeats.
References
Blesa, J.R., et al. Biochem. Cell Biol. 86(1):46-56(2008)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Shimokawa, T., et al. Int. J. Oncol. 29(2):381-386(2006)Yang, C.S., et al. Arch. Biochem. Biophys. 400(1):105-110(2002)
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