|Other Names||Ubiquitin-associated protein 2-like, Protein NICE-4, UBAP2L, KIAA0144, NICE4|
|Format||Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT-HSCs). Required for efficient formation of stress granules (PubMed:29395067).|
|Cellular Location||Cytoplasm, Stress granule|
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Provided below are standard protocols that you may find useful for product applications.
UBAP2L contains 1 UBA domain and has 3 named isoforms. UBA domains are a commonly occurring sequence motif of approximately 45 amino acid residues that are found in diverse proteins involved in the ubiquitin/proteasome pathway, DNA excision-repair, and cell signalling via protein kinases. The function of this protein is not known.
Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Wang, Y.L., et al. J. Biol. Chem. 283(49):33808-33815(2008)Olsen, J.V., et al. Cell 127(3):635-648(2006)Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
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