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TOMM40 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O96008 |
|---|---|
| Clone Names | 101008280 |
| Gene ID | 10452 |
|---|---|
| Other Names | Mitochondrial import receptor subunit TOM40 homolog, Protein Haymaker, Translocase of outer membrane 40 kDa subunit homolog, p385, TOMM40, C19orf1, PEREC1, TOM40 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TOMM40 |
|---|---|
| Synonyms | C19orf1, PEREC1, TOM40 |
| Function | Channel-forming protein essential for import of protein precursors into mitochondria (PubMed:15644312, PubMed:31206022). Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by forming a complex with BCAP31 and mediating the translocation of Complex I components from the cytosol to the mitochondria (PubMed:31206022). |
| Cellular Location | Mitochondrion outer membrane; Multi-pass membrane protein. Note=Associates with the mitochondria- associated ER membrane via interaction with BCAP31 |
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Provided below are standard protocols that you may find useful for product applications.
Background
TOMM40 is the channel-forming subunit of the translocaseof the mitochondrial outer membrane (TOM) complex that is essentialfor protein import into mitochondria (Humphries et al., 2005[PubMed 15644312]).
References
Shen, L., et al. Neuroimage 53(3):1051-1063(2010)Sebastiani, P., et al. Science (2010) In press :Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Seshadri, S., et al. JAMA 303(18):1832-1840(2010)Ma, L., et al. BMC Med. Genet. 11, 55 (2010) :
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