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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   MED30 Antibody (Center) Blocking Peptide   

MED30 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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  • CITATIONS
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Product Information
Primary Accession Q96HR3
Clone Names 110826253
Additional Information
Gene ID 90390
Other Names Mediator of RNA polymerase II transcription subunit 30, Mediator complex subunit 30, TRAP/Mediator complex component TRAP25, Thyroid hormone receptor-associated protein 6, Thyroid hormone receptor-associated protein complex 25 kDa component, Trap25, MED30, THRAP6, TRAP25
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MED30
Synonyms THRAP6, TRAP25
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Cellular Location Nucleus.
Tissue Location Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
Research Areas
Citations (0)

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Background

The multiprotein TRAP/Mediator complex facilitates geneexpression through a wide variety of transcriptional activators.MED30 is a component of this complex that appears to be metazoanspecific (Baek et al., 2002 [PubMed 11909976]).

References

Rienzo, M., et al. Biochim. Biophys. Acta 1799(7):487-495(2010)Sato, S., et al. Mol. Cell 14(5):685-691(2004)Tomomori-Sato, C., et al. J. Biol. Chem. 279(7):5846-5851(2004)Sato, S., et al. J. Biol. Chem. 278(17):15123-15127(2003)Wang, Q., et al. J. Biol. Chem. 277(45):42852-42858(2002)

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$ 277.78
Cat# BP19149c
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