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LRRC39 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q96DD0 |
|---|---|
| Clone Names | 110726118 |
| Other Names | Leucine-rich repeat-containing protein 39, Densin hlg, LRRC39 |
|---|---|
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LRRC39 |
|---|---|
| Function | Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via an SRF-dependent pathway. Important for normal contractile function in heart. |
| Cellular Location | Cytoplasm, myofibril, sarcomere, M line {ECO:0000250|UniProtKB:D3ZXS4} |
| Tissue Location | Highly expressed in skeletal muscle and heart. Not detected in other tissues tested. EMBL; AY358131; AAQ88498.1; -; mRNA EMBL; AK096892; BAG53394.1; -; mRNA EMBL; AL445928; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; CH471097; EAW72965.1; -; Genomic_DNA EMBL; CH471097; EAW72966.1; -; Genomic_DNA EMBL; CH471097; EAW72968.1; -; Genomic_DNA EMBL; CH471097; EAW72969.1; -; Genomic_DNA EMBL; BC009613; AAH09613.1; -; mRNA CCDS; CCDS58014.1; -. [Q96DD0-2] CCDS; CCDS766.1; -. [Q96DD0-1] RefSeq; NP_001243314.1; NM_001256385.1. [Q96DD0-2] RefSeq; NP_001243315.1; NM_001256386.1. [Q96DD0-1] RefSeq; NP_001243316.1; NM_001256387.1. [Q96DD0-1] RefSeq; NP_653221.1; NM_144620.3. [Q96DD0-1] BioGRID; 126062; 12 IntAct; Q96DD0; 16 STRING; 9606.ENSP00000480740; - iPTMnet; Q96DD0; - PhosphoSitePlus; Q96DD0; - BioMuta; LRRC39; - DMDM; 74760781; - MassIVE; Q96DD0; - PaxDb; Q96DD0; - PeptideAtlas; Q96DD0; - PRIDE; Q96DD0; - ProteomicsDB; 76280; -. [Q96DD0-1] ProteomicsDB; 76281; -. [Q96DD0-2] Antibodypedia; 33693; 177 antibodies DNASU; 127495; - Ensembl; ENST00000342895; ENSP00000344470; ENSG00000122477. [Q96DD0-1] Ensembl; ENST00000370137; ENSP00000359156; ENSG00000122477. [Q96DD0-1] Ensembl; ENST00000370138; ENSP00000359157; ENSG00000122477. [Q96DD0-2] Ensembl; ENST00000620882; ENSP00000480740; ENSG00000122477. [Q96DD0-2] GeneID; 127495; - KEGG; hsa:127495; - UCSC; uc001dsw.3; human. [Q96DD0-1] CTD; 127495; - DisGeNET; 127495; - EuPathDB; HostDB:ENSG00000122477.12; - GeneCards; LRRC39; - HGNC; HGNC:28228; LRRC39 HPA; ENSG00000122477; Group enriched (heart muscle, skeletal muscle, tongue) neXtProt; NX_Q96DD0; - OpenTargets; ENSG00000122477; - PharmGKB; PA142671527; - eggNOG; KOG0619; Eukaryota GeneTree; ENSGT00940000158998; - HOGENOM; CLU_000288_18_8_1; - InParanoid; Q96DD0; - OMA; WETRIRR; - OrthoDB; 1085197at2759; - PhylomeDB; Q96DD0; - TreeFam; TF333627; - PathwayCommons; Q96DD0; - BioGRID-ORCS; 127495; 14 hits in 870 CRISPR screens ChiTaRS; LRRC39; human GeneWiki; LRRC39; - GenomeRNAi; 127495; - Pharos; Q96DD0; Tdark PRO; PR:Q96DD0; - Proteomes; UP000005640; Chromosome 1 RNAct; Q96DD0; protein Bgee; ENSG00000122477; Expressed in deltoid and 157 other tissues Genevisible; Q96DD0; HS GO; GO:0005737; C:cytoplasm; IBA:GO_Central GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central GO; GO:0031430; C:M band; IEA:UniProtKB-SubCell GO; GO:0004722; F:protein serine/threonine phosphatase activity; IBA:GO_Central GO; GO:0007165; P:signal transduction; IBA:GO_Central Gene3D; 3.80.10.10; -; 2 InterPro; IPR001611; Leu-rich_rpt InterPro; IPR003591; Leu-rich_rpt_typical-subtyp InterPro; IPR032675; LRR_dom_sf Pfam; PF13855; LRR_8; 2 SMART; SM00369; LRR_TYP; 6 PROSITE; PS51450; LRR; 7 1: Evidence at protein level; Alternative splicing; Coiled coil; Cytoplasm; Leucine-rich repeat; Muscle protein; Polymorphism; Reference proteome; Repeat CHAIN 1..335 /note="Leucine-rich repeat-containing protein 39" /id="PRO_0000232580" REPEAT 84..105 /note="LRR 1" REPEAT 107..128 /note="LRR 2" REPEAT 130..151 /note="LRR 3" REPEAT 153..176 /note="LRR 4" REPEAT 177..197 /note="LRR 5" REPEAT 200..221 /note="LRR 6" REPEAT 223..244 /note="LRR 7" REPEAT 246..267 /note="LRR 8" REPEAT 269..290 /note="LRR 9" COILED 10..47 /evidence="ECO:0000255" COMPBIAS 294..299 /note="Poly-Glu" VAR_SEQ 318..335 /note="DHQVNGSTTLPISINTDG -> ALQFCVCHGQILTIYTCMALEI (in isoform 2)" /evidence="ECO:0000305" /id="VSP_017913" VARIANT 121 /note="I -> L (in dbSNP:rs34920283)" /id="VAR_034087" SEQUENCE 335 AA; 38793 MW; BAACA9D75FE5B7A3 CRC64; MTENVVCTGA VNAVKEVWEK RIKKLNEDLK REKEFQHKLV RIWEERVSLT KLREKVTRED GRVILKIEKE EWKTLPSSLL KLNQLQEWQL HRTGLLKIPE FIGRFQNLIV LDLSRNTISE IPPGIGLLTR LQELILSYNK IKTVPKELSN CASLEKLELA VNRDICDLPQ ELSNLLKLTH LDLSMNDFTT IPLAVLNMPA LEWLDMGSNK LEQLPDTIER MQNLHTLWLQ RNEITCLPQT ISNMKNLGTL VLSNNKLQDI PVCMEEMANL RFVNFRDNPL KLKVSLPPSE GTDEEEEREL FGLQFMHTYI QESRRRADHQ VNGSTTLPIS INTDG |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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$ 277.78
Cat# BP19189a
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