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BEST3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8N1M1
Clone Names 110808002
Additional Information
Gene ID 144453
Other Names Bestrophin-3, Vitelliform macular dystrophy 2-like protein 3, BEST3, VMD2L3
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BEST3
Synonyms VMD2L3
Function Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Present in skeletal muscle and weakly in brain, spinal cord, bone marrow and retina.
Research Areas
Citations (0)

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BEST3 belongs to the bestrophin family of anion channels,which includes BEST1 (MIM 607854), the gene mutant in vitelliformmacular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes,BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins aretransmembrane (TM) proteins that share a homology region containinga high content of aromatic residues, including an invariantarg-phe-pro (RFP) motif. The bestrophin genes share a conservedgene structure, with almost identical sizes of the 8 RFP-TMdomain-encoding exons and highly conserved exon-intron boundaries.Each of the 4 bestrophin genes has a unique 3-prime end of variablelength (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al.,2003 [PubMed 12907679]).


Marsey, L.L., et al. J. Physiol. (Lond.) 587 (PT 10), 2211-2224 (2009) :Qu, Z.Q., et al. J. Biol. Chem. 282(24):17460-17467(2007)Tsunenari, T., et al. J. Biol. Chem. 278(42):41114-41125(2003)Stohr, H., et al. Eur. J. Hum. Genet. 10(4):281-284(2002)Marquardt, A., et al. Hum. Mol. Genet. 7(9):1517-1525(1998)

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$ 277.78
Cat# BP19190a
Availability: 2 weeks
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