TEKT2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UIF3 |
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Clone Names | 100603257 |
Gene ID | 27285 |
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Other Names | Tektin-2, Tektin-t, Testicular tektin, Testicular tektin B1-like protein, TEKTB1, Tektin-B1, TEKT2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TEKT2 (HGNC:11725) |
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Function | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme (PubMed:36191189). Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. |
Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q922G7}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:Q922G7} Note=Colocalized with CCDC172 at the perinuclear region {ECO:0000250|UniProtKB:Q922G7} |
Tissue Location | Expressed at high levels in testis, trachea and fetal lung, and at lower levels in ovary, pituitary, adult lung, fetal brain and fetal kidney. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene product belongs to the tektin family ofproteins. Tektins comprise a family of filament-forming proteinsthat are coassembled with tubulins to form ciliary and flagellarmicrotubules. This gene is expressed in the testis and its proteinis localized to the flagella of the sperms, indicating that it mayplay a role in spermatogenesis.
References
Zuccarello, D., et al. Hum. Reprod. 23(4):996-1001(2008)Tanaka, H., et al. Mol. Cell. Biol. 24(18):7958-7964(2004)Iguchi, N., et al. Mol. Hum. Reprod. 8(6):525-530(2002)Wolkowicz, M.J., et al. Biol. Reprod. 66(1):241-250(2002)
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