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PMF1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6P1K2 |
|---|---|
| Clone Names | 110901058 |
| Gene ID | 100527963;11243 |
|---|---|
| Other Names | Polyamine-modulated factor 1, PMF-1, PMF1 {ECO:0000312|EMBL:AAH650311} |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PMF1 {ECO:0000312|EMBL:AAH65031.1} |
|---|---|
| Function | Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT. |
| Cellular Location | Nucleus. Chromosome, centromere, kinetochore Note=Associated with the kinetochore |
| Tissue Location | Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver |
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Provided below are standard protocols that you may find useful for product applications.
Background
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT.
References
Aleman, A., et al. Clin. Cancer Res. 14(24):8236-8243(2008)Kline, S.L., et al. J. Cell Biol. 173(1):9-17(2006)Obuse, C., et al. Nat. Cell Biol. 6(11):1135-1141(2004)Wang, Y., et al. Biochem. J. 366 (PT 1), 79-86 (2002) :Wang, Y., et al. Biochem. J. 355 (PT 1), 45-49 (2001) :
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