|Other Names||N-myc-interactor, Nmi, N-myc and STAT interactor, NMI|
|Format||Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5.|
|Tissue Location||Expressed in all adult and fetal tissues except brain and skin. More abundant in fetal tissues especially liver|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
NMYC interactor (NMI) encodes a protein that interactswith NMYC and CMYC (two members of the oncogene Myc family), andother transcription factors containing a Zip, HLH, or HLH-Zipmotif. The NMI protein also interacts with all STATs except STAT2and augments STAT-mediated transcription in response to cytokinesIL2 and IFN-gamma. The NMI mRNA has low expression levels in allhuman fetal and adult tissues tested except brain and has highexpression in cancer cell line-myeloid leukemias. [provided byRefSeq].
Davila, S., et al. Genes Immun. 11(3):232-238(2010)Fillmore, R.A., et al. Int. J. Cancer 125(3):556-564(2009)Quaye, L., et al. Br. J. Cancer 100(6):993-1001(2009)Vega, A., et al. Gynecol. Oncol. 112(1):210-214(2009)Quaye, L., et al. Clin. Cancer Res. 14(18):5833-5839(2008)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.