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TMPRSS6 Antibody(N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8IU80
Clone Names 100427174
Additional Information
Gene ID 164656
Other Names Transmembrane protease serine 6, 3421-, Matriptase-2, TMPRSS6
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMPRSS6
Function Membrane-bound serine protease (PubMed:18976966, PubMed:20518742, PubMed:25156943, PubMed:25588876). Through the cleavage of cell surface HJV, a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis (PubMed:25156943, PubMed:18408718, PubMed:18976966).
Cellular Location Cell membrane; Single-pass type II membrane protein. Note=The processed, activated two-chains form is released in the extracellular space.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a type IItransmembrane serine proteinase that is found attached to the cellsurface. The encoded protein may be involved in matrix remodelingprocesses in the liver.

References

Altamura, S., et al. Biochem. J. 431(3):363-371(2010)Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)De Falco, L., et al. Hum. Mutat. 31 (5), E1390-E1405 (2010) :Tanaka, T., et al. Blood 115(1):94-96(2010)Lee, P. Acta Haematol. 122 (2-3), 87-96 (2009) :

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$ 277.78
Cat# BP19372a
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